Evaluating the status of vitamin 25(OH) D levels among females of all age groups in Karachi, Pakistan. Vitamin D

Abstract

Introduction: Vitamin D plays an important role in growth, metabolism and reproduction. Deficiency of this vitamin is highly prevalent globally and leads to various disorders besides different skeletal deformities. Women of different reproductive ages are at higher risk of developing bone diseases because of low vitamin D levels.

Objective: This study aimed to assess the prevalence of vitamin D deficiencies in females of different ages in Karachi, Pakistan

Methodology: A retrospective investigation of vitamin D levels during a six month period at the Clinical Lab, Al-Khidmat Diagnostic Center, Karachi; Pakistan was performed.  Serum vitamin 25(OH) D levels of 1035 female were measured by Electrochemiluminescence (ECL) assay. The data was analyzed through SPSS version 16.

Results: Among 1035 participants of different reproductive ages, 26.1% (n= 270) showed severe vitamin D deficiency, 44.3% (n=458) displayed mild to moderate Vitamin D deficiency while 29.7% (n=307) were having normal levels of serum vitamin D.

Results: The data of 1035 subjects was examined and the mean serum vitamin 25(OH) D levels of the studied subjects were found as 21.04±14.13 with the minimum and maximum range of 4.97ng/ml to 70.71ng/ml

Conclusion: 70.4 % of our studied population had lower levels of vitamin D representing that the majority of Pakistani womenfolk have vitamin D Deficiency.

Keywords: Vitamin 25 (OH) D levels, Female population, Karachi.