Prevalence and risk factors of Hepatitis B among pregnant women.

Abstract

Introduction: Globally Hep C virus (HBV) a public health problem account for 2 billion infection and 400 million of them were chronically infected^1,2,3. In Pakistan prevalence among general population is 4.3 % with carrier rate 3-5% (7-9 million) ⁴.  The prevalence of HBV among pregnant women 5% (range 0.6% to >20%) worldwide, leading mother to child transmission causing fetal and neonatal hepatitis, attributed for 30% to 50% of chronic carriers.

Methodology: A cross-sectional study was conducted among randomly selected 140pregnantwomen attended the antenatal clinic of the District hospital of Rahim-Yar-Khan in June-July 2013. Rapid diagnostic tests kits were used to access for HB surface antigen (HBsAg).  A face to face interview was carried out by using structured pre-tested questionnaire to obtain demographic and other information.

Results: 16(9.3%) out of 140 pregnant women were found to be positive for HBsAg, higher risk age group was 20-29 years 10(62.5%) , 16(100%) out of 16 infected women and 6(4.83%) out of 124 non-infected women had Negative history of HBV in Husband. Blood transfusion in last pregnancy was 14(87.5%) out of 16 infected women and 52(41.93%) out of 124 non-infected women. 10(62.5%) out of 16 infected women and 5(4.03%) out of 124 non-infected women has passed through dental procedures. Therefore, negative history of HBV in Husband, blood transfusion and dental procedures in last pregnancy were the most prevalent risk factors among infected women. Among the total 124, 76(61.29%) were vaccinated against HBV, while 0(0%) out of 16 infected women were not vaccinated.

Conclusion: Prevalence of the HBV among pregnant women in Rahim-Yar-Khan is of intermediate endemicity (11.4%). Past history of blood transfusion and HBV infected Husband was the most prevalent risk factor. Health education regarding risk factors, preventive measures should be given to pregnant women with the involvement of Lady Health Worker and mass media. Free screening and immunization of pregnant women should be incorporated in antenatal and postnatal program of hospital.