Prevalence of types of arthritis and its association with biochemical parameters among pre- and post-menopausal women in different cities of Pakistan.

Abstract

Introduction: The prevalence of arthritis among both pre and post menopausal is alarmingly high. Old age, gender, obesity, unhealthy life style, poor nutrition, less physical activity, genetics, lack of knowledge about disease, lack if education are the factors which are strongly associated with onset of arthritis.

Objective: To document prevalence of different types of arthritis and its association with biochemical parameters among pre- and post-menopausal women in different cities of Pakistan.

Methodology: A total of 300 females’ patients who were diagnosed as case of arthritis from different aetiology, during April 2022 to September 2022, aged above 40 years were enrolled for this cross-sectional observational questionnaire and laboratory-based study. Their demographic and disease-related biochemical parameters were recorded and analysed.

Results: Over all prevalence of rheumatoid arthritis was high (39%) among both pre- and post-menopausal females. Biochemical laboratory analysis showed mean low (11.90 ± 2.18) level of haemoglobin. 66.6% and 60.6 % of the female patients were seropositive for Rheumatoid factor (RF) and Anti Cyclic Citrullinated Protein (Anti-CCP) which is clinical characteristics of Arthritis patients.

Conclusion: Women with different type of arthritis have border line mean levels of biochemical parameters which indicate co-morbidities like diabetes, cardiovascular and renal diseases, hypertension, obesity and osteoporosis.

Keywords: Post-menopausal, rheumatoid, psoriatic, osteoarthritis, biochemical parameters.