Analysis of the relationship between age, gender, site and frequency of different grades of astrocytoma.

Abstract

Objective: To examined the relationship among age, gender, location, and the frequency of different grades of astrocy-toma.
Methodology: This cross-sectional study was conducted in the pathology department of Basic Medical Sciences Insti-tute, Jinnah Postgraduate Medical Centre Karachi, Sindh; between 01-01-2019 to 31-12-2022. The study comprised 60 cases of astrocytoma. Biopsy samples of different grades of Astrocytoma were extensively investigated and included in the current research, taking into consideration their patients’ age, demographic characteristics, clinical information and histological findings. This study reviewed and approved by Institutional Review Board (IRB) of JPMC. The data was an-alyzed using IBM-SPSS version 23.0, utilizing the Pearson Chi-Square test of independence. The P-value of 0.05 was set as statistically significant.
Results: A total of sixty astrocytic tumour cases were investigated. As per the findings of this investigation, the mean age of study participants was 31.5 years, ranging from 4 to 65 years. Male outnumber (34, 56.6%) female (26, 43.3%). The frontal lobe (31.7%), posterior fossa (16.7), and parietal region (11.7) were among the more frequently afflicted sites.
Conclusion: Diffuse astrocytoma was the most frequently observed, while anaplastic astrocytic tumours were the least prevalent. The occurrence of high-grade astrocytic tumors was found to be more common in males compared to fe-males.

Keywords: Dentistry practice, Germ Cell and Embryonal Tumours, Neuroectodermal Tumours, Neuroepithelial, Glioma,