Comparison of Central Corneal Thickness Measurements Using Contact and Non-contact Pachymetry Devices in Glaucoma Patients

Abstract

Objective: To explore the relationship between contact and non-contact pachymetry methods in measuring central corneal
thickness among patients diagnosed with primary open-angle glaucoma.
Methodology: After ethical approval, written permission was obtained from all eligible participants after providing full details
about the procedure, risks, and benefits of the study for this cross-sectional study. Central corneal thickness was
calculated by contact method using Nidek Al scan biometer ultrasound measurement & by non- contact methods using
Nidek Al scan biometer optical measurement, TOMEY TMS 5 slit corneal topographer, and REXXAN SPM-700 specular
microscope. All collected data was digitized for use in the research analysis.
Results: The mean ± standard deviation of age was 57.90±12.19 years. In the distribution of gender, 44.0% were male
and 56.0% were female. A statistically significant correlation was observed between contact and non-contact pachymetry
measurements of central corneal thickness, with Pearson’s correlation coefficient calculated at r = 0.773 (P < 0.05).
Conclusion: A positive significant linear correlation was noted between contact and non-contact pachymetry devices in
the measurement of central corneal thickness.
Key words: Contact Pachymetry, Corneal Thickness, Open Angle Glaucoma, non-contact Pachymetr